Biorevitalization is gaining traction in aesthetic clinics as a non-volumising injectable treatment designed to restore the skin's hydration, elasticity, and tone. Unlike dermal fillers or volumising agents, biorevitalization treatment enhances skin quality from within, offering natural-looking results. This article explores biorevitalization before and after results, what practitioners and clients can expect, and the clinical factors that influence outcomes.
What Biorevitalization Can Improve
Biorevitalization is a targeted injectable therapy designed to restore the skin's physiological function through hydration and regeneration rather than volumization. Its primary mechanism involves intradermal delivery of biologically active compounds commonly non-crosslinked hyaluronic acid, polynucleotides, peptides, and amino acids stimulating fibroblast activity and enhancing dermal matrix repair.
1. Crepey Texture
Crepey skin is characterized by a thin, finely wrinkled surface with reduced dermal density, often exacerbated by age-related collagen loss, chronic dehydration, and photodamage. Biorevitalization improves skin density and texture by replenishing dermal hyaluronic acid stores and triggering new collagen synthesis. Repeated sessions promote smoother skin microrelief, particularly in fragile areas prone to crepey texture.
2. Fine Lines and Superficial Wrinkles
Unlike dermal fillers, which volumise tissue, biorevitalization smooths superficial lines by enhancing skin hydration and tensile strength from within. The increase in extracellular matrix proteins, especially Type I collagen and elastin, results in visibly firmer skin with reduced wrinkling across high-mobility zones such as the periorbital and perioral regions.
3. Dullness and Uneven Tone
Oxidative stress, poor microcirculation, and barrier impairment can all contribute to a lacklustre skin appearance. Biorevitalization reactivates dermal metabolism and improves capillary perfusion, leading to better oxygenation and nutrient delivery. The outcome is a more even, luminous complexion with reduced signs of fatigue or environmental damage.
4. Loss of Elasticity
Elastosis is a hallmark of chronically aged skin. Biorevitalization supports the gradual recovery of elasticity by activating fibroblasts and dermal remodeling. Hyaluronic acid enhances water retention within the dermis, while polynucleotides stimulate long-term tissue repair which is critical for restoring skin stretch and recoil properties.
5. High-Impact Treatment Areas
Biorevitalization shows particular efficacy in anatomically delicate areas where volume-based treatments may be contraindicated or less desirable. These include:
Periorbital (under-eye) region: Addresses early creepiness and dehydration without the risk of Tyndall effect or puffiness.
Neck: Improves horizontal necklines and restores firmness in an area where skin is often thin and mobile.
Décolleté: Enhances hydration and texture in the chest area, reducing sun-induced pigmentation and fine wrinkling.
Hands: Rejuvenates dorsal hand skin by improving thickness and reducing the visibility of tendons and veins.
6. Mechanistic Focus: Hydration and Collagen Stimulation
Unlike fillers or bio stimulators that aim to volumize or lift, revitalization is distinct in its approach. Its action is biochemical rather than structural, aimed at optimizing dermal function. The treatment achieves subtle but measurable rejuvenation by restoring moisture balance and supporting collagen integrity ideal for clients who prioritize skin quality over contour modification.
Before and After Results: What to Look For
High-quality biorevitalization before and after images reflect the treatment's ability to restore skin vibrancy and resilience. Practitioners should look for the following visible changes:
- Increased skin radiance and glow
- Smoother skin texture with reduced fine lines
- Improved tone and elasticity
- Plumper, more hydrated appearance without puffiness
In clinic settings, consistent angles, neutral lighting, and the absence of makeup are crucial for capturing reliable before and after documentation. These images are essential not only for marketing but for helping clients track their progress and understand the regenerative nature of the treatment.
Timeline for Visible Results
clients can expect a progressive improvement in skin condition following their initial biorevitalization injections. The treatment does not deliver immediate transformations but offers cumulative benefits:
- After 1 session: Subtle hydration, mild improvement in the glow
- After 2–4 sessions: Noticeable enhancement in firmness, texture, and tone
- Peak results: Typically seen 4 to 8 weeks after completing the full protocol
Long-term maintenance can sustain results and prevent regression due to environmental or intrinsic ageing factors.
How Many Sessions Are Needed?
The number of sessions required depends on the client’s baseline skin quality, the product used, and individual goals. However, the standard bio revitalisation protocol includes:
- Initial course: 2 to 4 sessions spaced 2 to 4 weeks apart
- Maintenance: Once every 6 to 9 months, depending on age, skin condition, and lifestyle factors
Aquashine biorevitalization and similar products containing hyaluronic acid and peptides are commonly used in structured protocols. Polynucleotide-based treatments may be preferred for enhanced collagen support in older or more damaged skin.
Ideal Patient Profiles
Biorevitalization treatment is suitable for a wide demographic, but it is especially recommended for clients with:
- Early signs of skin ageing
- Fine lines and superficial wrinkles
- Uneven or dull skin tone
- Sun-damaged skin
- Thin or wrinkled skin around the eyes or neck
- Post-procedure skin recovery (e.g. post-laser or microneedling)
It is also ideal for individuals preparing for an event who desire a refreshed appearance without volumizing effects.
What Influences Biorevitalization Results?
Several clinical and lifestyle factors can affect the outcomes of biorevitalization before and after comparisons:
- Product used: Different products offer different mechanisms. HA-based solutions like Jalupro hydrate and plump, while polynucleotides like Plinest promote cell regeneration.
- Age and skin condition: Younger skin responds faster, while mature skin may need more sessions.
- Lifestyle: Smoking, alcohol, poor hydration, and sun exposure can limit results.
- Post-care compliance: Following biorevitalization aftercare instructions, such as avoiding the sun, heat, or active skincare for a few days post-treatment, is essential for optimum recovery.
Biorevitalization Benefits: Setting Realistic Expectations
It is crucial to counsel clients that biorevitalization is not a substitute for volumising fillers or surgical facelifts. Instead, its benefits lie in skin quality improvements that develop over time. Practitioners should set the following expectations:
- Natural, subtle improvement in hydration, glow, and tone
- Cumulative results rather than instant transformation
- Best suited for prevention or early intervention rather than correction of severe ageing or volume loss
Those expecting dramatic changes after a single session may be better candidates for alternative therapies or should be prepared for a full course.
Biorevitalization Price Considerations
The cost of biorevitalization treatments varies based on the number of sessions, the area treated, and the product used. On average, UK prices range as follows:
When comparing biorevitalization prices, clients should consider the product quality, clinic reputation, and whether aftercare support is included. Searching for "biorevitalization near me" can help identify qualified local providers with transparent pricing and positive patient outcomes.
Best Biorevitalization Products
Not all products are created equal. Practitioners should select products based on clinical evidence, patient needs, and personal experience. Commonly used biorevitalization products include:
- Aquashine: Known for combining HA with peptides
- Jalupro: Offers both classic and HMW versions
- Plinest: A polynucleotide-based option for collagen stimulation
Selecting the right product plays a significant role in determining how effective the biorevitalization facial outcomes will be.
Conclusion
Biorevitalization offers a valuable, regenerative approach to skin rejuvenation without the volumizing effects associated with dermal fillers. It supports long-term skin health, glow, and resilience, making it an excellent addition to any aesthetic practice.
For medical aestheticians seeking to deliver clinically proven results with minimal downtime, biorevitalization injections are a versatile solution. From under-eyes to the décolleté, clients benefit from subtle improvements that feel natural and build confidence.
To master biorevitalization techniques, join our Regenerative Medicine Masterclass. Get hands-on insights and protocol-based training. Their expert-led courses can help you elevate your biorevitalization outcomes and deliver real, measurable skin transformation.
FAQs
How long does it take for biorevitalization to work?
Biorevitalization treatment typically shows mild improvements, such as enhanced hydration and skin glow, within the first 7–10 days. More visible changes in skin texture, tone, and elasticity are usually observed after 2–4 sessions, with peak results appearing 4–8 weeks after completing the protocol.
Is biorevitalization effective?
Yes, biorevitalization is clinically effective for improving hydration, firmness, and skin tone. It stimulates collagen production and supports dermal regeneration, especially in areas like the under-eyes, neck, décolleté, and hands. Biorevitalization before and after comparisons consistently show smoother, more radiant skin.
How many sessions of biorevitalization are needed?
Most patients require a course of 2 to 4 sessions, spaced 2 to 4 weeks apart, depending on skin condition and treatment goals. For maintenance, a session every 6 to 9 months is often recommended to sustain results.
How much does biorevitalization cost?
Biorevitalization prices in the UK vary based on the product used and the treatment area. On average, a single session may cost between €150 to €350. Full treatment protocols typically range from €450 to €900. Searching for biorevitalization near me can help you find local clinics with transparent pricing.
What not to do after biorevitalization?
Aftercare is essential for optimal biorevitalization results. Avoid sun exposure, vigorous exercise, alcohol, and applying active skincare products (like retinoids or acids) for at least 24–48 hours post-treatment. Follow all biorevitalization after care instructions provided by your practitioner.
Is biorevitalization the same as filler?
No, biorevitalization is not the same as a filler. While fillers add volume and shape to specific facial areas, biorevitalization focuses on improving skin quality through hydration and collagen stimulation. It delivers a more natural and subtle rejuvenation without altering facial structure.
References
- De Sanctis Pecora F, Benedetti B, Zerbinati N. Skin biorevitalisation with hyaluronic acid. PMFA Journal. https://www.thepmfajournal.com/features/features/post/skin-biorevitalisation-with-hyaluronic-acid. Accessed May 27, 2025.
- Sparavigna A, Tenconi B. Cutaneous Biorevitalization with Injective Treatments. Clinical, Cosmetic and Investigational Dermatology. 2019;12:681–688. doi:10.2147/CCID.S215186. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502127/. Accessed May 27, 2025.