Male patients are increasingly turning to Botox, not for a frozen, wrinkle-free look, but to subtly smooth expression lines, look more rested, and maintain a confident appearance that aligns with their natural facial structure. Yet treating male faces with Botox isn’t simply about using higher doses or targeting the same injection sites as women. It requires an understanding of male-specific anatomy, aesthetic preferences, and functional movement patterns.
For aesthetic practitioners, case-based learning provides one of the most effective ways to understand the unique considerations of injecting men. This article explores several real-world male Botox before and after scenarios, focusing on strategic dosing, common treatment areas, and practical injection techniques that support natural-looking results while avoiding common pitfalls like feminization or asymmetry.

Why Case Studies Matter in Male Botox
Male patients typically have thicker skin, stronger facial muscles, broader foreheads, and flatter brow positions. They often seek treatment not to eliminate wrinkles entirely, but to reduce harsh lines that may convey stress, fatigue, or anger. Because of these distinctions, Botox for men must be adapted thoughtfully, with a focus on maintaining masculine features while minimizing visible aging signs.
Case studies provide a practical lens through which these strategies can be understood. Reviewing dosage patterns, injection sites, and post-treatment results offers invaluable insight for injectors who want to deliver subtle, effective results without compromising the patient’s natural appearance. HubMed Ed is an excellent aesthetic medicine learning platform where you can find courses and other learning materials that can improve your career.
Case #1: Forehead + Glabella Treatment
Patient: 48-year-old male executive concerned about heavy lines
Baseline: Prominent horizontal creases and deep “11s” between brows
Treatment Strategy:
- Glabella: 60 units across the corrugator and procerus muscles
- Forehead: 30 units, applied in two horizontal rows with 1.5 cm spacing
Before: Horizontal lines remained visible during conversation; expressions highlighted deep creases
After: Lines visibly softened; forehead movement retained—no feminization or eyebrow arching
Injection Approach:
- Placed glabella units evenly to neutralize heavy line formation
- Injected forehead conservatively with microdoses from mid-forehead up to preserve muscle control
Key Takeaway: Men often need higher doses in the glabella; 60–80 units is typical, while forehead treatment stays moderate. Use at least 2 cm of clearance above the brow to avoid ptosis.

Case #2: Crow’s-Feet & Lateral Eye Wrinkles
Patient: 55-year-old man with dynamic lateral wrinkles
Baseline: Fine lines present during laughter and natural expression
Plan:
- 20 units per side into lateral orbicularis oculi
- Focus on the outer third, avoiding inner eyelids
Results:
Lines softened effectively without limiting eye function or giving a feminine appearance
Technical Notes:
- Thick male orbicularis often absorbs full 20–30 units per side
- Stay lateral to avoid affecting eyelid tone
Key Takeaway: Men need slightly higher dosing and must avoid over-treating inner eye areas to maintain character and function.

Case #3: Masseter Treatment in Men
Patient: 40-year-old client clenching jaw and desiring weakening
Baseline: Noticeable masseter hypertrophy and bruxism
Plan:
- 45 units per masseter via three injection sites
- Touch-up appointment scheduled at 4 weeks
Results:
Over 8 weeks, the jawline softened and grinding diminished without losing structural projection
Technique Tips:
- Start moderate; adjust based on tissue response
- Observe muscle change over time before adding more units
Key Takeaway: Men’s masseters require incremental, cautious treatment to reduce volume while maintaining a masculine jawline.

Common Botox Injection Sites for Men
While Botox for men can be used in many areas of the face, there are several high-demand zones where men typically request treatment. These include:
- Forehead (Frontalis): This area is treated to reduce horizontal lines that deepen with age. In men, care must be taken to avoid arching the brows too high, which can appear unnatural.
- Glabellar lines (Corrugators and Procerus): Often called “frown lines,” these vertical creases between the brows are one of the most common concerns among male patients. Treating this area can help the patient appear less angry or intense.
- Crow’s feet (Orbicularis oculi): Men may develop deep lines around the eyes, especially if they squint or smile broadly. Conservative Botox in this region can freshen the appearance without affecting genuine expression.
- Masseter muscle (Jawline): Male patients often seek Botox in the masseters for either jawline contouring or bruxism (teeth grinding). While slimming may not be the goal, softening a bulky jaw can improve facial symmetry.
- Bunny lines (nasal sidewall): Less common but still requested, these lines can be softened with a small number of units, typically in men who show strong nasal scrunching.
Technique Tips Based on Case Studies
Practitioners treating male patients must often deviate from the “standard” Botox injection patterns used for women. While foundational anatomy remains the same, the application varies in key ways.
- Men usually require higher doses. Due to denser musculature, male patients typically need more units to achieve the same level of relaxation seen in female patients.
- Adjust injection angles and spacing. Thicker skin and bulkier muscles may warrant deeper or more lateral injections. For more information, refer to our Botox injection training.
- Assess movement carefully before injecting. Observe the patient at rest and while expressing emotion. Men often have more pronounced muscle asymmetry, particularly in the glabella or crow’s feet area.
- Involve the patient in planning. Many men new to Botox fear looking overdone or “plastic.” Using visual aids like male Botox before-and-after images can guide them toward choosing realistic, conservative outcomes.
These nuanced adjustments help practitioners deliver results that align with masculine aesthetic ideals, defined features, rested expressions, and visible but softened movement, rather than complete muscle paralysis.
Where Do Most Men Get Botox?
The most popular treatment areas for male patients include:
- Forehead lines
- Glabellar lines (“11s”)
- Crow’s feet
- Masseter/jaw area
- Chin (for dimpling)
- Bunny lines (less common)
These areas tend to be prioritized because they address common aging concerns, especially expression lines that give an impression of fatigue or irritation. Forehead and glabellar lines are the most frequent starting points for first-time male Botox patients.

Where Should Men Not Get Botox?
While technically Botox can be used in many areas, there are a few zones where caution is warranted in male patients:
- Too close to the brow: Injecting too low on the forehead can cause brow ptosis (drooping), which is especially noticeable in men with heavier brow anatomy.
- Around the mouth: Botox near the lips or smile lines is used sparingly in men, as it can impact speech and smile dynamics if not done precisely.
- Neck (in younger male patients): Unless treating platysmal bands or chin dimpling, Botox in the neck region is typically avoided in younger men, as it doesn’t align with common male aesthetic goals.
FAQ
How long does Botox last on a man?
Results usually last 3–5 months, with male metabolism often dissipating effects faster due to muscle mass.
Is Botox for men worth it?
When performed correctly, Botox for men can drastically reduce visible aging signs and enhance confidence without feminizing features.
What is the best alternative for Botox?
Neuromodulators like Dysport® or Xeomin® offer similar results, though dosing equivalencies differ.
Does insurance cover Botox?
Cosmetic Botox is not covered, but treatments for bruxism or migraines may qualify under certain plans.
How much does Botox cost for a man?
Costs are generally higher for men since treatments often require more units, typically $500–$1,000+ per session depending on geographic location and provider.
Conclusion
Providing Botox for male patients demands a blend of science and subtlety. These case studies, forehead/glabella smoothing, crow's feet reduction, and masseter slimming, show how strategic, tailored BOT treatments help men look fresh and confident while maintaining their distinct, masculine features.
Use the lessons from these cases to shape your consultation process, customize injection sites, and build layered treatment plans. Enhancing male aesthetics with cautious, informed Botox application builds trust and delivers visible results that resonate without compromising identity.
To deepen your expertise in male-centered treatment, check out our Masterclass in Aesthetic Treatments for Men, a resource designed to train injectors in gender-specific strategies that deliver natural, satisfying outcomes.
Sources
- Flynn TC. Botox in men. Dermatol Ther. 2007;20(6):407-413. doi:10.1111/j.1529-8019.2007.00156.x https://pubmed.ncbi.nlm.nih.gov/18093014/
- Keaney TC, Alster TS. Botulinum toxin in men: review of relevant anatomy and clinical trial data. Dermatol Surg. 2013;39(10):1434-1443. doi:10.1111/dsu.12302 https://pubmed.ncbi.nlm.nih.gov/24090254/
- Hall DB, Kim LR. Male Rejuvenation: Injectables. Facial Plast Surg Clin North Am. 2024;32(3):425-435. doi:10.1016/j.fsc.2024.02.007 https://pubmed.ncbi.nlm.nih.gov/38937000/